Rare ATGL haplotypes are associated with increased plasma triglyceride concentrations in the Greenland Inuit
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Citation for Previous Publication
Johansen, C. T., Gallinger, Z. R., Wang, J., Ban, M. R., Young, T. K., Bjerregaard, P., & Hegele, R. A. (2010). Rare ATGL haplotypes are associated with increased plasma triglyceride concentrations in the Greenland Inuit. International Journal of Circumpolar Health, 69(1), 3-12. https://doi.org/10.3402/ijch.v69i1.17427
Link to Related Item
<https://v2.sherpa.ac.uk/id/publication/22717>
Abstract
Description
"Objectives: To genotype common genetic variants found in the adipose triglyceride lipase (ATGL) gene and test them for association with cardiovascular disease risk factors in the Greenland Inuit. Study design: Candidate gene association study of discrete and quantitative traits related to cardiovascular health. Methods: ATGL was sequenced in 10 European subjects to identify DNA sequence variants. The identified polymorphisms were subsequently genotyped in a population-based cohort of 1,218 unrelated Greenland Inuit subjects, ascertained from the Greenland Population Study. Genotypes and reconstructed haplotypes were tested for association with cardiovascular disease risk factors using additive, dominant or recessive models, corrected for age, sex and body mass index." (as cited in abstract)
Item Type
http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/version/c_970fb48d4fbd8a85
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Language
en
Location
Greenland